ÌìÃÀ´«Ã½

Establish a strong foundation for commercially successful therapies and advance from concept to candidate with ÌìÃÀ´«Ã½'s integrated discovery biology services.

Accelerate pre-clinical drug discovery with ÌìÃÀ´«Ã½’s extensive offering of biochemical and cell-based assays. Our discovery biology services are built upon a foundation of deep expertise in biochemistry, signal transduction, and cell biology. Interested in discovery biology services? Request more information. 

Extensive biochemical assays

Leverage our portfolio of biochemical assays that includes >600 druggable protein targets, including kinases, proteases, phosphatases - and many other enzymes regulating cell survival and apoptosis, epigenetic and metabolic circuits, and protein homeostasis. Flexible assay formats range from HTS and high content profiling to sophisticated mechanism of action (MOA) studies.

In addition to extensive experience performing high throughput screening for broad kinase, epigenetic and protein homeostasis, new new biochemical and cell-based assays can be developed quickly using modern detection methods, including TR-FRET, FP, BRET, Flow-Cytometry, LC-MS/MS, and state-of-the-art compound delivery approaches (acoustic dispensing). New assays are tailored to meet your needs and fully validated with highly standardized procedures. Looking to talk about your discovery biology and biochemical assay needs? Get in touch with us today.

Comprehensive cell-based assays and bioassays

Our cell-based assays utilize a large in-house collection of stable cell lines as well as primary cells and whole human blood. We perform intracellular drug-target engagement assays, phosphoprotein accumulation, and protein degradation assays. Plus, we offer cytokine ELISA, cell proliferation, and multiplex flow cytometry assays. Want to know more? Start the conversation. 

The ÌìÃÀ´«Ã½ advantage 

We're committed to helping you accelerate pre-clinical discovery with our systematic approach, aligning biochemical profiling and cell-based screening activities. So, let's talk about your goals and how we can make a difference.